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白癜风:采用磨皮术和薄断层皮片移植进行色素再生。

Vitiligo: repigmentation with dermabrasion and thin split-thickness skin graft.

作者信息

Agrawal K, Agrawal A

机构信息

Department of Plastic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.

出版信息

Dermatol Surg. 1995 Apr;21(4):295-300. doi: 10.1111/j.1524-4725.1995.tb00176.x.

DOI:10.1111/j.1524-4725.1995.tb00176.x
PMID:7728478
Abstract

BACKGROUND

Vitiligo is a common benign condition of great concern. Though a large number of medical and surgical treatment methods are available, none of them is fully dependable in all the areas.

OBJECTIVE

Split-thickness skin grafting (STSG) has been used for the treatment of vitiligo for over three decades, but it did not gain popularity. This presentation evaluates the degree of repigmentation achieved with this technique, its complications, and drawbacks.

METHODS

A case series of 21 patients with 32 localized, stable, and refractory vitiligo patches treated institutionally by dermabrasion and thin STSG has been presented. The patients have been followed up for 1-6 years. Three patients lost to follow-up before 1 year have not been included.

RESULTS

The graft take was 100% in 27 patches and 90-95% in the remaining five. One hundred percent repigmentation was achieved in 22 patches and 90-95% in 10. Time taken for satisfactory color match was 4-9 months (average, 6.3 months). The complications encountered were all minor and did not affect the results.

CONCLUSION

This is a simple, outpatient procedure performed under local anesthesia resulting in an excellent color match on a long-term follow-up. This technique can be used over any part of the body, including the hair-bearing areas, without compromising the end results.

摘要

背景

白癜风是一种常见的备受关注的良性疾病。尽管有大量的医学和外科治疗方法,但没有一种在所有方面都是完全可靠的。

目的

分层皮片移植(STSG)已用于治疗白癜风三十多年,但并未得到广泛应用。本报告评估了该技术实现的色素沉着程度、其并发症和缺点。

方法

报告了一组21例患者的病例系列,这些患者有32个局限性、稳定且难治的白癜风斑块,在机构内接受了磨皮和薄分层皮片移植治疗。对患者进行了1至6年的随访。排除了1年内失访的3例患者。

结果

27个斑块的移植成功率为100%,其余5个为90 - 95%。22个斑块实现了100%的色素沉着,10个为90 - 95%。达到满意颜色匹配所需的时间为4至9个月(平均6.3个月)。遇到的并发症均为轻微并发症,未影响结果。

结论

这是一种在局部麻醉下进行的简单门诊手术,长期随访显示颜色匹配效果极佳。该技术可用于身体的任何部位,包括有毛发的区域,且不影响最终结果。

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Dermatol Surg. 1995 Apr;21(4):295-300. doi: 10.1111/j.1524-4725.1995.tb00176.x.
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