Dormer K J, Bryce G E, Hough J V
University of Oklahoma Health Sciences Center, Oklahoma City.
Otolaryngol Clin North Am. 1995 Feb;28(1):17-27.
In the selection of biomaterials for middle ear applications of implantable devices, certainly the site of implantation and the mass of the implant will dictate the choice of biomaterials. Hermetic sealing of an implant is best achieved by the use of metals, not polymers. Osteocompatibility of an ossicular implant can be enhanced by the incorporation of calcium phosphates such as hydroxyapatite coatings. Finally, osseointegration or osseofixation is neither necessary nor desirable for ossicular implants, because (1) they may need to be removed or replaced in the future and (2) their solid fixation to an ossicle is not necessary for the vibratory function of hearing amplification.
在为中耳植入式设备选择生物材料时，植入部位和植入物质量无疑会决定生物材料的选择。植入物的气密密封最好通过使用金属而非聚合物来实现。通过加入磷酸钙，如羟基磷灰石涂层，可以增强听骨植入物的骨相容性。最后，对于听骨植入物来说，骨整合或骨固定既非必要也不理想，原因如下：（1）它们未来可能需要移除或更换；（2）对于听力放大的振动功能而言，它们与听小骨的牢固固定并非必要。
