Hallén I P, Jorhem L, Lagerkvist B J, Oskarsson A
Toxicology Division Swedish National Food Administration, Uppsala.
Sci Total Environ. 1995 Apr 21;166:149-55. doi: 10.1016/0048-9697(95)04523-4.
Lead and cadmium levels were determined (with AAS) in blood and milk obtained at 6 weeks after delivery from women living in the vicinity of a copper and lead metal smelter and in a control area. Analysis of lead and cadmium were also performed in blood samples obtained at delivery. Accuracy of the analysis was confirmed by the analysis of quality control samples. In general, blood and milk levels of lead and cadmium were low in both areas. At 6 weeks after delivery the lead levels in blood and milk were 32 +/- 8 and 0.7 +/- 0.4 micrograms Pb/l, respectively (total mean +/- S.D., n = 75). Cadmium levels in blood and milk were 0.9 +/- 0.3 and 0.06 +/- 0.04 microgram Cd/l, respectively (n = 75). At delivery the lead levels in blood of women in the smelter area were higher, 38.7 micrograms Pb/l, than the blood lead levels in women from the control area, 32.3 micrograms Pb/l, (P < 0.001). At 6 weeks after delivery there was no difference in blood lead levels between the two groups. In contrast, the lead levels in milk were higher in women from the smelter area, 0.9 microgram Pb/l, than in women from the control area, 0.5 microgram Pb/l, (P < 0.001). No differences in blood cadmium levels were found between the two groups. Milk cadmium levels in women from the control area, 0.07 microgram Cd/l, were somewhat higher (P < 0.01) than in women from the smelter area, 0.05 microgram Cd/l.(ABSTRACT TRUNCATED AT 250 WORDS)
对居住在铜铅金属冶炼厂附近地区的妇女以及对照地区的妇女,在分娩后6周采集的血液和乳汁样本中(采用原子吸收光谱法)测定铅和镉含量。同时也对分娩时采集的血液样本进行铅和镉分析。通过对质量控制样本的分析确认了分析的准确性。总体而言,两个地区血液和乳汁中的铅和镉含量均较低。分娩后6周,血液和乳汁中的铅含量分别为32±8微克铅/升和0.7±0.4微克铅/升(总均值±标准差,n = 75)。血液和乳汁中的镉含量分别为0.9±0.3微克镉/升和0.06±0.04微克镉/升(n = 75)。在分娩时,冶炼厂地区妇女血液中的铅含量较高,为38.7微克铅/升,高于对照地区妇女的血铅水平32.3微克铅/升(P<0.001)。分娩后6周,两组之间的血铅水平没有差异。相比之下,冶炼厂地区妇女乳汁中的铅含量为0.9微克铅/升,高于对照地区妇女的0.5微克铅/升(P<0.001)。两组之间的血镉水平没有差异。对照地区妇女乳汁中的镉含量为0.07微克镉/升,略高于冶炼厂地区妇女的0.05微克镉/升(P<0.01)。(摘要截选至250字)