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酵母二号染色体某片段的序列显示出两个新基因，一个几乎完全是疏水的，另一个富含天冬酰胺-丝氨酸。

Sequence of a segment of yeast chromosome II shows two novel genes, one almost entirely hydrophobic and the other extremely asparagine-serine rich.

作者信息

Cusick M E

机构信息

Department of Medical Biochemistry & Genetics, Texas A&M College of Medicine, College Station 77843-1114.

出版信息

Yeast. 1994 Sep;10(9):1251-6. doi: 10.1002/yea.320100913.

DOI:10.1002/yea.320100913
PMID:7754714
Abstract

A 3.2 kb EcoRI fragment of yeast Saccharomyces cerevisiae was entirely sequenced. Two new open reading frames were identified. The first is extremely hydrophobic, and would likely be an integral membrane protein. It has significant similarity to only one reported gene, a gene of unknown function from Drosophila melanogaster. The second ORF is asparagine-rich and very serine-rich, with a remarkable stretch of nearly 26 consecutive asparagine residues comprised of the same codon. It has no significant similarity to any reported gene. The fragment maps to chromosome II on the left arm between the CDC27 and ILS1 loci.

摘要

对酿酒酵母的一个3.2 kb EcoRI片段进行了全序列测定。鉴定出两个新的开放阅读框。第一个具有极强的疏水性，可能是一种整合膜蛋白。它仅与一个已报道的基因具有显著相似性，该基因来自黑腹果蝇，功能未知。第二个开放阅读框富含天冬酰胺和丝氨酸，有一段由相同密码子组成的近26个连续天冬酰胺残基的显著延伸。它与任何已报道的基因均无显著相似性。该片段定位于II号染色体左臂上CDC27和ILS1基因座之间。

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1
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Yeast. 1994 Sep;10(9):1251-6. doi: 10.1002/yea.320100913.
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Yeast. 1992 Sep;8(9):761-8. doi: 10.1002/yea.320080909.
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