酵母第十一染色体左臂上一个17.5 kb DNA片段的序列鉴定出蛋白激酶基因ELM1、DNA引发酶基因PRI2、一个编码假定组蛋白的新基因以及七个新的开放阅读框。
The sequence of a 17.5 kb DNA fragment on the left arm of yeast chromosome XI identifies the protein kinase gene ELM1, the DNA primase gene PRI2, a new gene encoding a putative histone and seven new open reading frames.
作者信息
Purnelle B, Tettelin H, Van Dyck L, Skala J, Goffeau A
机构信息
Unité de Biochimie Physiologique, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.
出版信息
Yeast. 1993 Dec;9(12):1379-84. doi: 10.1002/yea.320091212.
PMID:8154189
Abstract
A 17.5 kb DNA fragment of chromosome XI, located between the genetic loci mif2 and mak11 was sequenced and analysed. Ten open reading frames were identified. Two of them are the previously sequenced genes ELM1 and PRI2, two (YKL253 and YKL256) show homologies to proteins from other organisms and one (YKL262) to yeast and mouse histone.
摘要
对位于遗传位点mif2和mak11之间的第XI号染色体上一段17.5 kb的DNA片段进行了测序和分析。鉴定出了10个开放阅读框。其中两个是先前已测序的基因ELM1和PRI2，两个（YKL253和YKL256）与其他生物体的蛋白质具有同源性，还有一个（YKL262）与酵母和小鼠组蛋白具有同源性。
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