Kao C H, Pan D Y, Wang S J, Chen G H
Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan, Republic of China.
Eur J Nucl Med. 1995 Feb;22(2):122-5. doi: 10.1007/BF00838941.
Forty-four patients with non-insulin-dependent diabetes mellitus (NIDDM) were included in this study. Radionuclide-labelled solid meals were used to calculate gastric emptying times (GETs). The carbon-14 urea breath test (14C-UBT) was used to diagnose Helicobacter pylori (HP) infection. The patients were separated into groups according to the following two criteria: (1) HP infection was diagnosed on the basis of a 14C-UBT value of > or = 1.5; (2) the GET was defined as abnormal when it was > or = 117.1 min. The results showed that 61% (27/44) of the NIDDM patients had an HP infection, and 59% (26/44) had an abnormal GET. The incidence of abnormal GET in positive 14C-UBT patients (62%) was higher than that in negative 14C-UBT patients (56%). Similarly, the incidence of positive 14C-UBT in abnormal GET cases (62%) was higher than that in normal GET cases (56%). However, according to chi-square tests the differences were not significant. In conclusion, no significant relationship between HP infection and GET was found in patients with NIDDM.
本研究纳入了44例非胰岛素依赖型糖尿病（NIDDM）患者。使用放射性核素标记的固体餐来计算胃排空时间（GETs）。采用碳-14尿素呼气试验（14C-UBT）诊断幽门螺杆菌（HP）感染。根据以下两个标准将患者分组：（1）14C-UBT值≥1.5时诊断为HP感染；（2）GET≥117.1分钟时定义为异常。结果显示，61%（27/44）的NIDDM患者有HP感染，59%（26/44）的GET异常。14C-UBT阳性患者中GET异常的发生率（62%）高于14C-UBT阴性患者（56%）。同样，GET异常病例中14C-UBT阳性的发生率（62%）高于GET正常病例（56%）。然而，根据卡方检验，差异无统计学意义。总之，在NIDDM患者中未发现HP感染与GET之间存在显著关系。
