一种胞壁质水解酶复合物对青霉素耐药而非青霉素敏感的肺炎链球菌菌株的培养物和细胞壁进行选择性裂解。
Selective lysis of cultures and cell walls of penicillin-resistant but not penicillin-susceptible Streptococcus pneumoniae strains by a murein hydrolase complex.
作者信息
Severin A, Tomasz A
机构信息
Laboratory of Microbiology, Rockefeller University, New York, New York 10021, USA.
出版信息
J Bacteriol. 1995 Jun;177(11):3316-9. doi: 10.1128/jb.177.11.3316-3319.1995.
Abstract
A murein hydrolase complex selectively lysed cultures of penicillin-resistant pneumococci and their cell walls in which the majority of muropeptide subunits were indirectly cross-linked through oligopeptide substituents (alanyl-alanine or alanyl-serine) on the epsilon-amino group of the stem peptide lysine residues. Walls of penicillin-susceptible strains were not hydrolyzed.
摘要
一种胞壁质水解酶复合物能选择性地裂解耐青霉素肺炎球菌及其细胞壁，在这些细胞壁中，大多数胞壁肽亚基通过茎肽赖氨酸残基ε-氨基上的寡肽取代基（丙氨酰-丙氨酸或丙氨酰-丝氨酸）间接交联。青霉素敏感菌株的细胞壁未被水解。
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