Donenko F V, Moroz L V
Vestn Ross Akad Med Nauk. 1995(4):14-6.
The impact of surgical treatment of Ehrlich's carcinoma on animals' survival was studied. Tumour removal on posttransplantation day 30 was shown to cause no increases in the longevity of the animals operated on as compared with those non-operated on (mean longevity was 59.9 and 62.2 days, respectively). The death causes of the animals operated on were metastases and relapses. On day 7 after transplantation, cyclophosphanum therapy of Ehrlich's carcinoma failed to prolong the animals' life. While 24 hours after tumour transplantation the longevity increased from 61.8 to 93.4 days. No therapeutical effects were shown to be associated with the influence of humoral factors of the host body on tumor growth. It was shown that the lack of these humoral factors resulted in interrupting tumor growth.
研究了艾氏癌手术治疗对动物存活的影响。结果显示，与未手术的动物相比，在移植后第30天切除肿瘤并未使接受手术的动物寿命延长（平均寿命分别为59.9天和62.2天）。接受手术的动物的死亡原因是转移和复发。移植后第7天，环磷酰胺治疗艾氏癌未能延长动物寿命。而在肿瘤移植后24小时，寿命从61.8天增加到了93.4天。未显示治疗效果与宿主身体体液因子对肿瘤生长的影响有关。结果表明，缺乏这些体液因子会导致肿瘤生长中断。
