五种脊椎动物线粒体转运RNA的比较。

A comparison of mitochondrial tRNAs in five vertebrates.

作者信息

Jukes T H

机构信息

Space Sciences Laboratory, University of California, Berkeley 94720, USA.

出版信息

J Mol Evol. 1995 May;40(5):537-40. doi: 10.1007/BF00166622.

DOI:10.1007/BF00166622

PMID:7783227

Abstract

Sequences of several vertebrate mitochondrial tRNAs were aligned and compared. The comparisons were made in pairs of the tRNAs for an identical amino acid. There are 22 genes for different tRNAs in each vertebrate mitochondrial DNA. The closet similarities were between rat and mouse, the next were between mammals, and the widest difference was between human or rat and Xenopus laevis. However, there were very wide variations between different amino acids in each set of comparisons. The time lapse for each percent of difference greatly increased with evolutionary separation. Most of the nucleotide substitutions appeared to be neutral in character.

摘要

对几种脊椎动物线粒体tRNA的序列进行了比对和比较。比较是在编码相同氨基酸的tRNA之间成对进行的。每个脊椎动物线粒体DNA中有22个不同tRNA的基因。大鼠和小鼠之间的相似性最高，其次是哺乳动物之间，而人类或大鼠与非洲爪蟾之间的差异最大。然而，在每组比较中，不同氨基酸之间存在非常大的差异。随着进化距离的增加，每百分比差异的时间间隔大幅增加。大多数核苷酸替换似乎是中性的。