单纯疱疹病毒在波斯纳-施洛斯曼综合征病因中的可能作用。

Possible role of herpes simplex virus in the origin of Posner-Schlossman syndrome.

作者信息

Yamamoto S, Pavan-Langston D, Tada R, Yamamoto R, Kinoshita S, Nishida K, Shimomura Y, Tano Y

机构信息

Department of Virology, Schepens Eye Research Institute, Boston, MA 02114, USA.

出版信息

Am J Ophthalmol. 1995 Jun;119(6):796-8. doi: 10.1016/s0002-9394(14)72788-6.

DOI:10.1016/s0002-9394(14)72788-6

PMID:7785697

Abstract

PURPOSE/METHODS: We conducted this study to determine if the herpesviruses are possible etiologic agents in Posner-Schlossman syndrome. We aspirated aqueous humor samples from patients during acute attacks of the syndrome. Ten normal aqueous humor specimens from patients undergoing cataract surgery were used as controls. DNA was extracted and subjected to polymerase chain reaction amplification and Southern blot hybridization.

RESULTS/CONCLUSION: All three specimens were positive for amplified genomic fragments of herpes simplex virus and negative for varicella-zoster virus and cytomegalovirus. Ten normal aqueous specimens were negative for all three. Herpes simplex virus may play a role in the origin of Posner-Schlossman syndrome.

摘要

目的/方法：我们开展这项研究以确定疱疹病毒是否为波斯纳-施洛斯曼综合征可能的病因。我们在该综合征急性发作期间从患者体内抽取房水样本。将接受白内障手术患者的10份正常房水标本用作对照。提取DNA并进行聚合酶链反应扩增和Southern印迹杂交。

结果/结论：所有3份标本单纯疱疹病毒基因组片段扩增均呈阳性，水痘-带状疱疹病毒和巨细胞病毒呈阴性。10份正常房水标本这三种病毒均呈阴性。单纯疱疹病毒可能在波斯纳-施洛斯曼综合征的发病中起作用。