在基于肉汤的系统中检测对两性霉素B耐药的念珠菌分离株。
Detection of amphotericin B-resistant Candida isolates in a broth-based system.
作者信息
Rex J H, Cooper C R, Merz W G, Galgiani J N, Anaissie E J
机构信息
Department of Internal Medicine, University of Texas Medical School, Houston, USA.
出版信息
Antimicrob Agents Chemother. 1995 Apr;39(4):906-9. doi: 10.1128/AAC.39.4.906.
Abstract
Because of the limited ability of the National Committee for Clinical Laboratory Standards proposed M27P methodology to detect resistance to amphotericin B by Candida isolates, we sought to identify alternative media and pH conditions that could reliably identify resistant isolates. Antibiotic Medium 3 broth (also known as Penassay broth) buffered to pH 5 or pH 7 produced superior results and readily identified a series of resistant isolates.
摘要
由于美国国家临床实验室标准委员会提出的M27P方法检测念珠菌分离株对两性霉素B耐药性的能力有限，我们试图确定能够可靠鉴定耐药分离株的替代培养基和pH条件。缓冲至pH 5或pH 7的3号抗生素肉汤（也称为青霉素检测肉汤）产生了更好的结果，并能轻松鉴定出一系列耐药分离株。
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