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用于在自由活动动物中进行细胞外神经元活动记录的微型微驱动器。

Miniature microdrive for extracellular recording of neuronal activity in freely moving animals.

作者信息

Korshunov V A

机构信息

CNRS-College de France, Laboratoire de Physiologie de la Perception de l'Action UMR-C9950, Paris, France.

出版信息

J Neurosci Methods. 1995 Mar;57(1):77-80. doi: 10.1016/0165-0270(94)00130-9.

DOI:10.1016/0165-0270(94)00130-9
PMID:7791367
Abstract

The new design of a removable miniature microdrive for extracellular recordings of single-unit activity in freely moving animals with high-impedance electrodes is presented. The construction permits very simple installation and removal of the microelectrodes, rapid fixation of the microdrive on the animals skull and rapid removal after recording. The microdrive provides vertical positioning of the electrode without rotations and lateral shifts, stable recordings of single units for several hours and the possibility to change the penetration track 20-30 times in the same animal. The 3.2-mm diameter of the microdrive cylinder permits the installation of several units simultaneously. The weight of the microdrive with the base is 115 mg. The microdrive permits penetrations to any desired depth.

摘要

本文介绍了一种新型可移动微型微驱动器的设计,该微驱动器用于使用高阻抗电极对自由活动动物的单单元活动进行细胞外记录。其结构允许非常简单地安装和移除微电极,能快速将微驱动器固定在动物头骨上,并在记录后快速移除。该微驱动器可实现电极的垂直定位,无旋转和横向偏移,能稳定记录单个单元数小时,并且有可能在同一只动物中改变刺入轨迹20至30次。微驱动器圆柱体的直径为3.2毫米,允许同时安装多个单元。带底座的微驱动器重量为115毫克。该微驱动器可穿透到任何所需深度。

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