Faruque M O, Khan M R, Rahman M M, Ahmed F
Institute of Nutrition and Food Science, University of Dhaka, Bangladesh.
Br J Nutr. 1995 Apr;73(4):625-32. doi: 10.1079/bjn19950064.
The present study was designed to investigate the relationship between smoking and antioxidant nutrient intake and status. Smoker (n 44) and non-smoker (n 44) male students attending Dhaka University, aged between 22 and 28 years and living in a University Hall of Residence, were selected for the present study. Mean age, body weight, BMI and blood pressure were similar for both the smokers and non-smokers. Mean energy, protein and fat intakes were similar for both groups. Smokers had lower intakes of dietary vitamin C, carotenes and Zn but only the difference in Zn intake was statistically significant. There was no significant difference between smokers and non-smokers for either serum vitamin A (retinol) or vitamin E (alpha-tocopherol) level. The plasma vitamin C level of smokers was significantly lower than that of non-smokers (P = 0.0004). Smokers had significantly lower serum Cu (P = 0.04) and higher serum Zn levels (P = 0.003). Further, a significant dose-response relationship between smoking and vitamin C status was observed. Linear-regression analysis showed a significantly positive correlation between dietary intake and plasma vitamin C values in non-smokers (r 0.50; P = 0.0005). On the contrary, no such association was observed in smokers. These findings suggest that smoking may cause an imbalance in antioxidant nutrient intake and status.
本研究旨在调查吸烟与抗氧化营养素摄入及状态之间的关系。本研究选取了达卡大学年龄在22至28岁之间、居住在大学宿舍的44名吸烟男学生和44名不吸烟男学生。吸烟者和不吸烟者的平均年龄、体重、BMI和血压相似。两组的平均能量、蛋白质和脂肪摄入量相似。吸烟者的膳食维生素C、胡萝卜素和锌摄入量较低，但只有锌摄入量的差异具有统计学意义。吸烟者和不吸烟者的血清维生素A（视黄醇）或维生素E（α-生育酚）水平均无显著差异。吸烟者的血浆维生素C水平显著低于不吸烟者（P = 0.0004）。吸烟者的血清铜水平显著较低（P = 0.04），而血清锌水平较高（P = 0.003）。此外，观察到吸烟与维生素C状态之间存在显著的剂量反应关系。线性回归分析显示，不吸烟者的膳食摄入量与血浆维生素C值之间存在显著正相关（r = 0.50；P = 0.0005）。相反，在吸烟者中未观察到这种关联。这些发现表明，吸烟可能导致抗氧化营养素摄入和状态失衡。
