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[哮喘和特应性皮炎中的细胞间黏附分子-1(ICAM-1)]

[The ICAM-1 cell adhesion molecule in asthma and atopic dermatitis].

作者信息

Sabbah A, Lauret M G

机构信息

Laboratoire d'Immuno-Allergologie, CHU, Angers, France.

出版信息

Allerg Immunol (Paris). 1994 Oct;26(8):283-8.

PMID:7802929
Abstract

Measurement of serum ICAM 1, an adhesion molecule, by an enzymo-immunological method, compared with IgE and IFN gamma in three groups of subjects (reference, asthma and atopic dermatitis) shows a statistically significant raised titre in the atopic dermatitis group (377 ng/ml) in comparison with the reference group (300.4 ng/ml). The titre of ICAM 1 in the asthma group (317 ng/ml) was not significantly different from that of the reference. The difference between the latter two groups may be more clearly seen if the measurements were made not in serum but instead in the liquid from broncho-alveolar lavage (LBA) for asthmatics.

摘要

采用酶免疫法测定血清中粘附分子ICAM - 1,并与三组受试者(参照组、哮喘组和特应性皮炎组)的IgE及干扰素γ进行比较,结果显示,与参照组(300.4 ng/ml)相比,特应性皮炎组(377 ng/ml)的ICAM - 1滴度在统计学上显著升高。哮喘组的ICAM - 1滴度(317 ng/ml)与参照组无显著差异。如果不是在血清中而是在哮喘患者的支气管肺泡灌洗(LBA)液中进行测量,后两组之间的差异可能会更明显。

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