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子宫内膜异位症与不孕:外源性脂质过氧化物在腹腔液中的作用

Endometriosis and infertility: the role of exogenous lipid peroxides in the peritoneal fluid.

作者信息

Arumugam K, Dip Y C

机构信息

Department of Obstetrics and Gynaecology, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Fertil Steril. 1995 Jan;63(1):198-9. doi: 10.1016/s0015-0282(16)57320-8.

DOI:10.1016/s0015-0282(16)57320-8
PMID:7805914
Abstract

OBJECTIVE

To determine if lipid peroxides were raised in the pelvic peritoneal fluid of patients with endometriosis.

DESIGN

Control study involving patients with and without endometriosis.

METHODS

The lipid peroxide (malondialdehyde) levels in the pelvic PF of 12 patients with moderate-to severe endometriosis, 15 patients with minimal-mild endometriosis and 13 patients with normal pelvises were compared.

RESULTS

The level of lipid peroxides were not affected by the presence nor the severity of endometriosis.

CONCLUSION

Accelerated lipid peroxidation does not appear to play a role in the causal relationship between endometriosis and infertility.

摘要

目的

确定子宫内膜异位症患者盆腔腹膜液中脂质过氧化物水平是否升高。

设计

涉及有或无子宫内膜异位症患者的对照研究。

方法

比较了12例中重度子宫内膜异位症患者、15例轻度子宫内膜异位症患者和13例盆腔正常患者盆腔腹膜液中脂质过氧化物(丙二醛)水平。

结果

脂质过氧化物水平不受子宫内膜异位症的存在与否及严重程度影响。

结论

脂质过氧化加速似乎在子宫内膜异位症与不孕的因果关系中不起作用。

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