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低剂量区域辐射致癌的剂量-反应关系。

Dose-response relationship for radiation carcinogenesis in the low-dose region.

作者信息

Cohen B L

机构信息

University of Pittsburgh, PA 15260.

出版信息

Int Arch Occup Environ Health. 1994;66(2):71-5. doi: 10.1007/BF00383360.

Abstract

Evidence that low-level radiation substantially enhances the effectiveness of repair mechanisms is summarized. This finding destroys the theoretical basis (there is no other basis) for use of a linear-no threshold dose-response relationship to estimate the cancer risk of exposure to low-level radiation. Such a methodology will exaggerate the risk. This conclusion is further supported by epidemiological evidence and by studies of the effects of radon exposure in the home, which are reviewed.

摘要

低水平辐射能显著增强修复机制有效性的证据已被总结。这一发现摧毁了使用线性无阈值剂量反应关系来估计低水平辐射致癌风险的理论基础(不存在其他基础)。这种方法会夸大风险。这一结论得到了流行病学证据以及家庭中氡暴露影响研究的进一步支持,这些研究将进行综述。

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