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1
The functional role of CD8+ T helper type 2 cells.CD8+ 2型辅助性T细胞的功能作用。
J Exp Med. 1995 Jan 1;181(1):5-7. doi: 10.1084/jem.181.1.5.
2
The IL4- induced switch of CD8+ T cells to a TH2 phenotype and its possible relationship to the onset of AIDS.白细胞介素4诱导CD8 + T细胞向TH2表型转变及其与艾滋病发病的可能关系。
Res Immunol. 1994 Oct-Dec;145(8-9):643-5; discussion 645-6. doi: 10.1016/s0923-2494(05)80047-1.
3
AIDS--beyond helper T cells.艾滋病——超越辅助性T细胞
Lancet. 1996 Sep 7;348(9028):631. doi: 10.1016/S0140-6736(05)65070-2.
4
Specifying helper T cell fates during immunity.在免疫过程中确定辅助性T细胞的命运。
J Pediatr Gastroenterol Nutr. 2008 Apr;46 Suppl 1:E19-20. doi: 10.1097/01.mpg.0000313832.47207.0e.
5
Self-reactive anti-class II T helper type 2 cell lines derived from gold salt-injected rats trigger B cell polycolonal activation and transfer autoimmunity in CD8-depleted normal syngeneic recipients.从注射金盐的大鼠中获得的自身反应性抗II类辅助性T2细胞系可触发B细胞多克隆激活，并在CD8细胞耗竭的同基因正常受体中转移自身免疫性。
Eur J Immunol. 1995 Jul;25(7):1972-9. doi: 10.1002/eji.1830250726.
6
Distinct roles for B7-1 and B7-2 determinants during priming of effector CD8+ Tc1 and regulatory CD4+ Th2 cells for contact hypersensitivity.在接触性超敏反应中，B7-1和B7-2决定簇在效应性CD8+ Tc1细胞和调节性CD4+ Th2细胞启动过程中的不同作用。
J Immunol. 1997 Nov 1;159(9):4217-26.
7
Effects of TH1 and TH2 cytokines on CD8+ cell response against human immunodeficiency virus: implications for long-term survival.TH1和TH2细胞因子对CD8 +细胞抗人类免疫缺陷病毒反应的影响：对长期生存的意义。
Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):11135-9. doi: 10.1073/pnas.92.24.11135.
8
The role of Th2 type CD4+ T cells and Th2 type CD8+ T cells in asthma.Th2型CD4+ T细胞和Th2型CD8+ T细胞在哮喘中的作用。
Immunol Cell Biol. 1996 Apr;74(2):206-8. doi: 10.1038/icb.1996.29.
9
IL-4 and IL-13 receptors: Roles in immunity and powerful vaccine adjuvants.IL-4 和 IL-13 受体：在免疫中的作用和强大的疫苗佐剂。
Cytokine Growth Factor Rev. 2014 Aug;25(4):437-42. doi: 10.1016/j.cytogfr.2014.07.010. Epub 2014 Jul 23.
10
T helper type 1/T helper type 2 cytokines and T cell death: preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of CD4+ T cells from human immunodeficiency virus-infected persons.1型辅助性T细胞/2型辅助性T细胞细胞因子与T细胞死亡：白细胞介素12对人免疫缺陷病毒感染者CD4+T细胞活化诱导的及CD95（FAS/APO-1）介导的凋亡的预防作用
J Exp Med. 1995 Dec 1;182(6):1759-67. doi: 10.1084/jem.182.6.1759.

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1
Interleukin-12-responding asialoGM1+CD8+ central memory-type T cells as precursor cells for interferon-gamma-producing killer T cells.作为产生干扰素-γ的杀伤性T细胞前体细胞的白细胞介素-12反应性去唾液酸GM1⁺CD8⁺中央记忆型T细胞
Cancer Sci. 2006 Nov;97(11):1236-41. doi: 10.1111/j.1349-7006.2006.00306.x. Epub 2006 Sep 5.
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Novel insights into the aetiology and pathophysiology of increased airway inflammation during COPD exacerbations.对慢性阻塞性肺疾病急性加重期气道炎症增加的病因学和病理生理学的新见解。
Respir Res. 2006 May 22;7(1):80. doi: 10.1186/1465-9921-7-80.
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Expression of complement receptor type 1 (CR1) on erythrocytes of paracoccidiodomycosis patients.副球孢子菌病患者红细胞上补体受体1（CR1）的表达
Mycopathologia. 2001;152(3):125-33. doi: 10.1023/a:1013123721376.
4
CD8-deficient SJL mice display enhanced susceptibility to Theiler's virus infection and increased demyelinating pathology.缺乏CD8的SJL小鼠对泰勒氏病毒感染的易感性增强，脱髓鞘病理改变增加。
J Neurovirol. 2001 Oct;7(5):409-20. doi: 10.1080/135502801753170264.
5
Host factors influencing viral persistence.影响病毒持续存在的宿主因素。
Philos Trans R Soc Lond B Biol Sci. 2000 Aug 29;355(1400):1031-41. doi: 10.1098/rstb.2000.0640.
6
Immunological principles of adverse drug reactions: the initiation and propagation of immune responses elicited by drug treatment.药物不良反应的免疫学原理：药物治疗引发的免疫反应的启动与传播。
Drug Saf. 2000 Dec;23(6):483-507. doi: 10.2165/00002018-200023060-00002.
7
Predominant type-2 response in infants with respiratory syncytial virus (RSV) infection demonstrated by cytokine flow cytometry.通过细胞因子流式细胞术证明呼吸道合胞病毒（RSV）感染婴儿中存在主要的2型反应。
Clin Exp Immunol. 2000 Aug;121(2):332-8. doi: 10.1046/j.1365-2249.2000.01297.x.
8
Interleukin-10-induced CD8 cell proliferation.白细胞介素-10诱导的CD8细胞增殖。
Immunology. 1999 Sep;98(1):80-9. doi: 10.1046/j.1365-2567.1999.00828.x.
9
Characterization of the memory/activated T cells that mediate the long-lived host response against tuberculosis after bacillus Calmette-Guérin or DNA vaccination.卡介苗或DNA疫苗接种后介导宿主对结核病长期免疫反应的记忆/活化T细胞的特征分析。
Immunology. 1999 Aug;97(4):573-81. doi: 10.1046/j.1365-2567.1999.00840.x.
10
Reduced production of both Th1 and Tc1 lymphocyte subsets in atopic dermatitis (AD).特应性皮炎（AD）中Th1和Tc1淋巴细胞亚群的产生均减少。
Clin Exp Immunol. 1999 Jan;115(1):1-5. doi: 10.1046/j.1365-2249.1999.00773.x.

本文引用的文献

1
Switch of CD8 T cells to noncytolytic CD8-CD4- cells that make TH2 cytokines and help B cells.CD8 T细胞转变为产生TH2细胞因子并辅助B细胞的非细胞溶解性CD8-CD4-细胞。
Science. 1993 Jun 18;260(5115):1802-5. doi: 10.1126/science.8511588.
2
Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals.无症状的人类免疫缺陷病毒血清阳性个体中白细胞介素-2和白细胞介素-4产生的变化。
J Clin Invest. 1993 Mar;91(3):759-65. doi: 10.1172/JCI116294.
3
CD8+ cytotoxic T cell therapy of cytomegalovirus and HIV infection.巨细胞病毒和HIV感染的CD8 + 细胞毒性T细胞疗法。
Curr Opin Immunol. 1993 Aug;5(4):484-91. doi: 10.1016/0952-7915(93)90027-p.
4
A TH1-->TH2 switch is a critical step in the etiology of HIV infection.辅助性T细胞1（TH1）向辅助性T细胞2（TH2）的转变是HIV感染病因学中的关键一步。
Immunol Today. 1993 Mar;14(3):107-11. doi: 10.1016/0167-5699(93)90208-3.
5
Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance.蠕虫感染会导致病毒特异性CD8 + 细胞毒性T细胞和Th1细胞因子反应降低，以及病毒清除延迟。
Proc Natl Acad Sci U S A. 1993 Feb 1;90(3):948-52. doi: 10.1073/pnas.90.3.948.
6
Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: differential CTL responses to HIV-1 and Epstein-Barr virus in late disease.人类免疫缺陷病毒1型（HIV-1）感染不同阶段HIV-1特异性细胞毒性T淋巴细胞（CTL）反应的定量分析：疾病晚期对HIV-1和爱泼斯坦-巴尔病毒的不同CTL反应
J Exp Med. 1993 Feb 1;177(2):249-56. doi: 10.1084/jem.177.2.249.
7
Th2-like CD8+ T cells showing B cell helper function and reduced cytolytic activity in human immunodeficiency virus type 1 infection.在1型人类免疫缺陷病毒感染中表现出B细胞辅助功能且细胞溶解活性降低的Th2样CD8 + T细胞。
J Exp Med. 1994 Aug 1;180(2):489-95. doi: 10.1084/jem.180.2.489.
8
Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens.口服耐受：通过口服自身抗原对动物和人类器官特异性自身免疫性疾病的免疫机制及治疗
Annu Rev Immunol. 1994;12:809-37. doi: 10.1146/annurev.iy.12.040194.004113.
9
Acquisition of lymphokine-producing phenotype by CD4+ T cells.CD4 + T细胞获得产生淋巴因子的表型。
Annu Rev Immunol. 1994;12:635-73. doi: 10.1146/annurev.iy.12.040194.003223.
10
CD8+ T lymphocytes provide helper activity for IgE synthesis in human immunodeficiency virus-infected patients with hyper-IgE.在人类免疫缺陷病毒感染的高IgE患者中，CD8 + T淋巴细胞为IgE合成提供辅助活性。
J Exp Med. 1995 Jan 1;181(1):423-8. doi: 10.1084/jem.181.1.423.

The functional role of CD8+ T helper type 2 cells.

作者信息

Seder R A, Le Gros G G

机构信息

Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-1892.

出版信息

J Exp Med. 1995 Jan 1;181(1):5-7. doi: 10.1084/jem.181.1.5.

DOI:10.1084/jem.181.1.5
PMID:7807025
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2191843/
Abstract
摘要