Imwidthaya P
Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Mycopathologia. 1994 Sep;127(3):135-7. doi: 10.1007/BF01102912.
Penicillium marneffei is endemic in Southeast Asia. Although Thailand is a country in this region, penicillosis marneffei was rare. It was found occasionally in immunocompromised patients. With the increasing incidence of HIV seropositivity penicillosis marneffei emerged as one of the major problems in HIV infected patients residing in Thailand. The common presenting signs were fever, anemia, hepatomegaly, lymphadenopathy. productive cough and a common skin manifestation as molluscum contagiosum-like lesions. The diseases should be considered in Thais and immunocompromised travelers with a history of visiting Thailand. Because the disease is potentially curable, prompt diagnosis and treatment will lead to better prognosis.
马尔尼菲青霉菌在东南亚地区为地方性流行。尽管泰国是该地区的一个国家,但马尔尼菲青霉病却很罕见,偶尔在免疫功能低下的患者中发现。随着HIV血清阳性率的上升,马尔尼菲青霉病成为泰国HIV感染患者的主要问题之一。常见的临床表现为发热、贫血、肝肿大、淋巴结病、咳痰,以及一种常见的皮肤表现,即传染性软疣样损害。对于有泰国旅行史的泰国人和免疫功能低下的旅行者,应考虑患有该病。由于该病有可能治愈,及时诊断和治疗将带来更好的预后。