Srivastava P K, Udono H
Department of Biological Sciences, Fordham University, Bronx, New York 10458.
Curr Opin Immunol. 1994 Oct;6(5):728-32. doi: 10.1016/0952-7915(94)90076-0.
Heat shock proteins (HSPs) are associated with a broad spectrum of peptides derived from the cells from which they are isolated. Vaccination with such HSP-peptide complexes elicits protective immunity against tumors or other cells used as the source of HSPs. These observations suggest that HSP-peptide complexes are suitable as vaccines against cancers and infectious diseases.
热休克蛋白（HSPs）与从其分离的细胞衍生的多种肽相关。用此类热休克蛋白-肽复合物进行疫苗接种可引发针对肿瘤或用作热休克蛋白来源的其他细胞的保护性免疫。这些观察结果表明，热休克蛋白-肽复合物适合作为抗癌症和传染病的疫苗。
