Hechemy K, Stevens R W, Gaafar H A
J Clin Microbiol. 1976 Jul;4(1):82-6. doi: 10.1128/jcm.4.1.82-86.1976.
Specific aggregation of latex particles due to antigen-antibody reaction occurred only when antigen was latex bound, as found in a study using Escherichia coli 0111:B4 extract. Maximum serological sensitivity was achieved when free antigen was present in a narrow range of ratios with the bound antigen.
如在一项使用大肠杆菌0111:B4提取物的研究中所发现的,仅当抗原与乳胶结合时,才会因抗原-抗体反应发生乳胶颗粒的特异性聚集。当游离抗原与结合抗原以窄范围的比例存在时,可实现最大血清学敏感性。