Kim R, Baggott B B, Rose S, Shar A O, Mallory D L, Lasky S S, Kressloff M, Faccenda L Y, Reynolds J C
Department of Medicine, University of Pittsburgh, Pennsylvania.
Gastroenterology. 1995 Feb;108(2):360-6. doi: 10.1016/0016-5085(95)90061-6.
BACKGROUND/AIMS: The inability to precisely measure the area of Barrett's metaplasia has impaired the study of its natural history and response to therapy. This study used a novel computer program that creates two-dimensional maps of the esophagus allowing for calculation of the area of Barrett's metaplasia.
Endoscopic photographs of Barrett's models and patients were obtained by independent endoscopists. The program transformed the photographs into maps, and the area of Barrett's metaplasia was calculated.
Using models, calculated areas correlated with actual areas (r = 0.96) with an overall error of 5.2%. Color, size, shape, diameter of the model, or endoscopist's experience did not affect the accuracy. Accuracy did improve by decreasing the interval between photographs from 4 cm (10.0% error) to 2 cm (4.8% error). In patients, area calculations from maps created by independent technicians correlated precisely (r = 0.99) at 1-cm (n = 22) and 2-cm (n = 40) intervals. Independent endoscopists correlated precisely in producing photographs for map construction (r = 0.99; n = 20).
This novel computer technology produces two-dimensional maps of Barrett's metaplasia that can be used to accurately calculate area. Minimal interobserver variability in obtaining photographs is found.
背景/目的：无法精确测量巴雷特化生的面积阻碍了对其自然史及治疗反应的研究。本研究使用了一种新型计算机程序，该程序可创建食管的二维地图，从而能够计算巴雷特化生的面积。
由独立的内镜医师获取巴雷特模型和患者的内镜照片。该程序将照片转换为地图，并计算巴雷特化生的面积。
使用模型时，计算出的面积与实际面积相关（r = 0.96），总体误差为5.2%。模型的颜色、大小、形状、直径或内镜医师的经验均不影响准确性。通过将照片间隔从4厘米（误差10.0%）减小到2厘米（误差4.8%），准确性确实有所提高。在患者中，由独立技术人员创建的地图所计算出的面积在间隔为1厘米（n = 22）和2厘米（n = 40）时精确相关（r = 0.99）。独立的内镜医师在为地图构建拍摄照片时精确相关（r = 0.99；n = 20）。
这种新型计算机技术可生成巴雷特化生的二维地图，用于准确计算面积。在获取照片时观察者间差异最小。
