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8种经典方剂对家兔血小板聚集影响的研究

[Study of platelet aggregation affected by 8 classical recipes in rabbit].

作者信息

Ge Z Y, Lin C R, Zhou Y W

机构信息

Xi-yuan Hospital, China Academy of TCM, Beijing.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 Aug;14(8):489-90.

PMID:7841759
Abstract

Arachidonic acid can induce platelet aggregation in rabbits in vitro. The experimental model was designed to observe inhibitory effect of 8 classical recipes of activating blood circulation to remove the stasis on platelet aggregation in vitro. The results showed that each one of 8 classical recipes has inhibitory effect on platelet aggregation in vitro in various degree. Among them, Gexia Zhuyu Tang (GZT), Shentong Zhuyu Tang (SZT) and Shaofu Zhuyu Tang (SFZT) were more effective. The results suggested that inhibitory effect of platelet aggregation produced by 8 classical recipes might be one of mechanisms of blood stasis treatment.

摘要

花生四烯酸在体外可诱导兔血小板聚集。设计该实验模型以观察8首经典活血化瘀方对体外血小板聚集的抑制作用。结果显示,8首经典方均对体外血小板聚集有不同程度的抑制作用。其中,膈下逐瘀汤(GZT)、身痛逐瘀汤(SZT)和少腹逐瘀汤(SFZT)效果更佳。结果提示,8首经典方产生的血小板聚集抑制作用可能是其治疗血瘀证的机制之一。

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