Guglielmi G, Ji C, Massoud T F, Kurata A, Lownie S P, Viñuela F, Robert J
Endovascular Therapy Service, University of California, Los Angeles Medical Center.
Neuroradiology. 1994 Oct;36(7):547-50. doi: 10.1007/BF00593518.
A new technique for surgical construction of experimental lateral saccular aneurysms on the common carotid artery of swine is described. It involves end-to-side suturing of an isolated segment of vein to an artery. During a short period of parent artery clamping, an elliptical arteriotomy is fashioned through the open-ended vein graft, the open end of which is subsequently tied and clamps are removed to form an aneurysmal vein pouch. The principal advantage of this technique is the short period of vascular clamping necessary to isolate a segment of the parent artery. This prevents severe endothelial injury and prolonged postoperative vasospasm, both of which may promote intra-aneurysmal thrombosis. Narrow- or wide-necked aneurysms can be created. Steps in the surgical construction of this model are detailed, and specific advantages of using swine are highlighted.
描述了一种在猪颈总动脉上手术构建实验性外侧囊状动脉瘤的新技术。该技术包括将一段分离的静脉端侧缝合至动脉。在短暂夹闭母动脉期间，通过开放端的静脉移植物制作一个椭圆形动脉切口，随后将其开放端结扎并移除夹子以形成一个动脉瘤性静脉囊袋。该技术的主要优点是隔离母动脉一段所需的血管夹闭时间短。这可防止严重的内皮损伤和术后长时间的血管痉挛，这两者都可能促进动脉瘤内血栓形成。可以创建窄颈或宽颈动脉瘤。详细介绍了该模型手术构建的步骤，并突出了使用猪的具体优点。
