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[一种测定人体皮肤表面胆固醇含量的方法及其应用前景。II. 银屑病]

[A method of determination of cholesterol contents on the surface of the human skin and prospects of its use. II. Psoriasis].

作者信息

Fortinskaia E S, Torkhovskaia T I, Sharapova G Ia, Loginova T K, Khalilol E M

出版信息

Klin Lab Diagn. 1994 Sep-Oct(5):15-7.

PMID:7850227
Abstract

A noninvasive method for cholesterol extraction from the surface layers of the epidermis is suggested. Levels of cholesterol and its fractions were measured in extracts obtained from the foci of psoriasis and apparently intact skin of 105 patients with psoriasis. Cholesterol levels were found noticeably increased, mainly at the expense of its free fraction in involved foci and in apparently intact skin. A conclusion is made on the good informative value of the suggested method.

摘要

提出了一种从表皮表层提取胆固醇的非侵入性方法。对105例银屑病患者的银屑病病灶及外观正常皮肤提取物中的胆固醇及其组分水平进行了测定。发现胆固醇水平显著升高,主要是以受累病灶及外观正常皮肤中游离胆固醇组分的增加为代价。得出该方法具有良好信息价值的结论。

相似文献

1
[A method of determination of cholesterol contents on the surface of the human skin and prospects of its use. II. Psoriasis].[一种测定人体皮肤表面胆固醇含量的方法及其应用前景。II. 银屑病]
Klin Lab Diagn. 1994 Sep-Oct(5):15-7.
2
[A method of determination of cholesterol contents on the surface of the human skin and prospects of its use. I. Atherosclerosis].[一种测定人体皮肤表面胆固醇含量的方法及其应用前景。I. 动脉粥样硬化]
Klin Lab Diagn. 1994 Sep-Oct(5):12-5.
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[Free and esterified epidermal cholesterol in psoriasis].
Vestn Ross Akad Med Nauk. 1995(3):57-9.
4
[Features of distribution of free and esterified cholesterol in the epidermis, biological membranes and plasma lipoproteins in psoriasis].
Klin Lab Diagn. 1996 Jul-Aug(4):38-43.
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Role of Skin pH in Psoriasis.皮肤pH值在银屑病中的作用。
Curr Probl Dermatol. 2018;54:108-114. doi: 10.1159/000489524. Epub 2018 Aug 21.
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Psoriatic lesional skin exhibits an aberrant expression pattern of interferon regulatory factor-2 (IRF-2).银屑病皮损皮肤表现出干扰素调节因子2(IRF-2)的异常表达模式。
J Pathol. 2003 Jan;199(1):107-14. doi: 10.1002/path.1263.
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[Lipid peroxidation processes in epidermis of patients with psoriasis].
Voen Med Zh. 2000 Jul;321(7):40-3, 95.
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Noninvasive characterization of human stratum corneum of undiseased skin of patients with atopic dermatitis and psoriasis as studied by Fourier transform Raman spectroscopy.通过傅里叶变换拉曼光谱法对特应性皮炎和银屑病患者未患病皮肤的人体角质层进行无创表征。
Biopolymers. 2001;62(3):141-6. doi: 10.1002/bip.1006.
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[Epidermal lipids in psoriasis].[银屑病中的表皮脂质]
Ann Univ Mariae Curie Sklodowska Med. 1998;53:173-8.
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Skin surface imaging of psoriasis vulgaris by using an electron paramagnetic resonance spin probe.利用电子顺磁共振自旋探针进行寻常型银屑病的皮肤表面成像。
J Dermatol Sci. 2016 Jan;81(1):71-3. doi: 10.1016/j.jdermsci.2015.10.006. Epub 2015 Oct 20.

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