伴有抗体产生增强的慢性黏膜皮肤念珠菌病。
Chronic mucocutaneous candidiasis accompanied by enhanced antibody production.
作者信息
Takeya K, Nomoto K, Matsumoto T, Miyake T, Himeno K
出版信息
Clin Exp Immunol. 1976 Sep;25(3):497-500.
Abstract
In four cases of chronic mucocutaneous candidiasis (CMCC) enhanced antibody production against candida antigen was detected in association iwth depressed cellular immunity. These patients showed extremely high agglutinin titre to candida antigen, while they were unable to mount delayed hypersensitivity reactions to candida antigen, tuberculin-purified protein derivative (PPD) or to dinitrochlorobenzene (DNCB). They also showed prolonged survival of skin homografts. There was no correlation between migration inhibitory factor (MIF) production and blast transformation in response to candida antigen.
摘要
在4例慢性黏膜皮肤念珠菌病（CMCC）患者中，检测到针对念珠菌抗原的抗体产生增强，同时伴有细胞免疫功能低下。这些患者对念珠菌抗原的凝集素滴度极高，然而他们对念珠菌抗原、结核菌素纯化蛋白衍生物（PPD）或二硝基氯苯（DNCB）均无法产生迟发型超敏反应。他们的皮肤同种异体移植物存活时间也延长。对念珠菌抗原的迁移抑制因子（MIF）产生与母细胞转化之间没有相关性。
相似文献
1
Chronic mucocutaneous candidiasis accompanied by enhanced antibody production.伴有抗体产生增强的慢性黏膜皮肤念珠菌病。
Clin Exp Immunol. 1976 Sep;25(3):497-500.
2
[Clinical and immunological study of 2 cases of systemic candidiasis].2例系统性念珠菌病的临床与免疫学研究
Boll Ist Sieroter Milan. 1976 Mar;55(71):65-72.
3
4
Use of transfer factor in patients with depressed cellular immunity and chronic infection.转移因子在细胞免疫功能低下及慢性感染患者中的应用。
Birth Defects Orig Artic Ser. 1975;11(1):431-5.
5
Restoration of cell-mediated immune responses with transfer factor.用转移因子恢复细胞介导的免疫反应。
Birth Defects Orig Artic Ser. 1975;11(1):441-4.
6
Immunodeficiencies in chronic muco-cutaneous candidosis.慢性黏膜皮肤念珠菌病中的免疫缺陷
Immunology. 1972 May;22(5):775-87.
7
8
Effect of transfer factor on lymphocyte function in anergic patients.转移因子对无反应性患者淋巴细胞功能的影响。
J Clin Invest. 1972 Nov;51(11):2948-58. doi: 10.1172/JCI107119.
9
Specific inhibition of in vitro Candida-induced lymphocyte proliferation by polysaccharidic antigens present in the serum of patients with chronic mucocutaneous candidiasis.慢性黏膜皮肤念珠菌病患者血清中存在的多糖抗原对体外念珠菌诱导的淋巴细胞增殖的特异性抑制作用。
J Clin Invest. 1978 Nov;62(5):1005-13. doi: 10.1172/JCI109204.
10
Lymphocyte stimulation in Candida albicans infections.白色念珠菌感染中的淋巴细胞刺激
Sabouraudia. 1974 Mar;12(1):87-94.
引用本文的文献
1
Black yeasts and their filamentous relatives: principles of pathogenesis and host defense.黑色酵母菌及其丝状亲缘菌：发病机制与宿主防御原理
Clin Microbiol Rev. 2014 Jul;27(3):527-42. doi: 10.1128/CMR.00093-13.
2
Antibody immunity and invasive fungal infections.抗体免疫与侵袭性真菌感染
Infect Immun. 1995 Nov;63(11):4211-8. doi: 10.1128/iai.63.11.4211-4218.1995.
3
Cutaneous defenses against dermatophytes and yeasts.皮肤对皮肤癣菌和酵母菌的防御。
Clin Microbiol Rev. 1995 Jul;8(3):317-35. doi: 10.1128/CMR.8.3.317.
4
Enhanced antibody responses induced by Candida albicans in mice.白色念珠菌在小鼠体内诱导增强的抗体反应。
Infect Immun. 1982 Dec;38(3):1102-8. doi: 10.1128/iai.38.3.1102-1108.1982.
5
Immunological observations before and after successful treatment of chronic mucocutaneous candidiasis with ketoconazole and transfer factor.酮康唑和转移因子成功治疗慢性黏膜皮肤念珠菌病前后的免疫学观察
Eur J Pediatr. 1984 Nov;143(1):45-8. doi: 10.1007/BF00442747.
6
Pathological observations in experimental candida infection of sensitized guinea pigs.致敏豚鼠实验性念珠菌感染的病理学观察
Mycopathologia. 1985 Sep;91(3):187-92. doi: 10.1007/BF00446299.
7
Mannan-specific and mannan-induced T-cell suppressive activity in patients with chronic mucocutaneous candidiasis.慢性黏膜皮肤念珠菌病患者中甘露聚糖特异性及甘露聚糖诱导的T细胞抑制活性
J Clin Immunol. 1987 Sep;7(5):400-9. doi: 10.1007/BF00917018.
8
Cell-mediated immune responses in mice infected with Fonsecaea pedrosoi.感染裴氏瓶霉的小鼠的细胞介导免疫反应。
Mycopathologia. 1979 Aug 31;68(1):9-15. doi: 10.1007/BF00490385.
9
Specific inhibition of in vitro Candida-induced lymphocyte proliferation by polysaccharidic antigens present in the serum of patients with chronic mucocutaneous candidiasis.慢性黏膜皮肤念珠菌病患者血清中存在的多糖抗原对体外念珠菌诱导的淋巴细胞增殖的特异性抑制作用。
J Clin Invest. 1978 Nov;62(5):1005-13. doi: 10.1172/JCI109204.
本文引用的文献
1
A study of Candida albicans agglutinins in human sera.一项关于人类血清中白色念珠菌凝集素的研究。
J Hyg (Lond). 1955 Dec;53(4):509-12. doi: 10.1017/s0022172400001005.
2
Immunological phenomena in leprosy and related diseases.麻风病及相关疾病中的免疫现象。
Adv Immunol. 1971;13:209-66. doi: 10.1016/s0065-2776(08)60185-6.
3
Chronic mucocutaneous candidiasis: model-building in cellular immunity.慢性黏膜皮肤念珠菌病：细胞免疫中的模型构建
Ann Intern Med. 1971 Jun;74(6):955-78. doi: 10.7326/0003-4819-74-6-955.
4
Immune abnormalities associated with chronic mucocutaneous candidiasis.与慢性黏膜皮肤念珠菌病相关的免疫异常。
Cell Immunol. 1973 Mar;6(3):348-61. doi: 10.1016/0008-8749(73)90035-x.
5
6
Chronic mucocutaneous candidiasis: T cell deficiency associated with B cell dysfunction in man.
Cell Immunol. 1974 Nov;14(2):215-25. doi: 10.1016/0008-8749(74)90207-x.
7
Immunodeficiencies in chronic muco-cutaneous candidosis.慢性黏膜皮肤念珠菌病中的免疫缺陷
Immunology. 1972 May;22(5):775-87.
Zotero 插件