Varney V A, Cumberworth V, Sudderick R, Durham S R, Mackay I S
Nose Clinic, Royal Brompton Hospital, London, UK.
Clin Otolaryngol Allied Sci. 1994 Jun;19(3):237-40. doi: 10.1111/j.1365-2273.1994.tb01222.x.
A total of 17 patients with yellow nail syndrome are described. Their symptoms, age of onset and severity are examined with particular reference to the presence of rhinosinusitis. Fourteen of the patients (83%) suffered severe rhinosinusitis, which pre-dated nail changes in four, coincided with yellow nails in six, and occurred later in the remaining patients. In general, patients responded poorly to conventional medical and surgical treatment, with the exception of functional endoscopic sinus surgery (FESS) which may be of value in these patients. The frequent association of rhinosinusitis with yellow nails may warrant its recognition as part of the syndrome. Careful inspection of the fingernails in all patients presenting with severe rhinosinusitis is warranted.
共描述了17例黄甲综合征患者。对他们的症状、发病年龄和严重程度进行了检查，特别提及了鼻窦炎的存在情况。14例患者（83%）患有严重鼻窦炎，其中4例鼻窦炎先于指甲改变出现，6例与黄甲同时出现，其余患者鼻窦炎在黄甲之后出现。一般来说，患者对传统药物和手术治疗反应不佳，但功能性鼻内镜鼻窦手术（FESS）可能对这些患者有价值。鼻窦炎与黄甲的频繁关联可能值得将其视为该综合征的一部分。对于所有患有严重鼻窦炎的患者，仔细检查指甲是必要的。
