Graziani A, Zoli M, Magalotti D, Grimaldi M, Gueli C, Pisi E
Istituto di Clinica Medica Generale e Terapia Medica, Università degli Studi di Bologna.
Minerva Med. 1994 Sep;85(9):461-6.
Evaluation of gallbladder and gastric emptying after ingestion of a saline enriched water ("Acqua Santa" di Chianciano) in comparison with a commercial oligomineral water.
A 40-minute blind prospective study.
The study was performed at the Terme of Chianciano (Siena) for subjects of group A and at the Institute of Clinica Medica Generale and Terapia Medica of the University of Bologna for subjects of group B.
Two groups of healthy subjects were studied. Each group consisted of 12 subjects without gallbladder disease.
Fasting subjects of group A ingested alternatively, for two consecutive mornings, 400 ml of the saline enriched water at the natural temperature of 33 degrees C or 400 ml of oligomineral water warmed to the same temperature. Subjects of group B ingested the same waters at 18 degrees C.
Gastric and gallbladder emptying were evaluated, after ingestion of the different waters, by means of ultrasonography.
In both groups gallbladder emptying was significantly higher after ingestion of the saline enriched water. On the other hand gastric emptying was similar with both waters.
This study demonstrated that saline enriched water determines a greater emptying of the gallbladder in comparison with an oligomineral water. This effects is not related to gastric emptying but rather it is due to a higher concentration of saline components and thus to their possible effect on gallbladder motility.
比较饮用富含盐分的水（奇安恰诺的“圣泉”水）和市售低矿化度水后胆囊及胃的排空情况。
一项40分钟的盲法前瞻性研究。
A组受试者的研究在奇安恰诺温泉（锡耶纳）进行，B组受试者的研究在博洛尼亚大学综合临床医学与医学治疗研究所进行。
研究了两组健康受试者。每组由12名无胆囊疾病的受试者组成。
A组空腹受试者在连续两个早晨交替饮用400毫升自然温度为33摄氏度的富含盐分的水或400毫升加热至相同温度的低矿化度水。B组受试者在18摄氏度下饮用相同的水。
在饮用不同的水后，通过超声检查评估胃和胆囊的排空情况。
两组饮用富含盐分的水后胆囊排空均显著更高。另一方面，两种水的胃排空情况相似。
本研究表明，与低矿化度水相比，富含盐分的水会使胆囊排空更多。这种效应与胃排空无关，而是由于盐分成分浓度更高，从而可能对胆囊运动产生影响。
