Sun L, Spiehler V
Clin Chem. 1976 Dec;22(12):2029-31.
Patients' sera were analyzed for digoxin by using two different radioimmunoassays and an enzyme immunoassay. Quantitative results obtained by enzyme immunoassay (I) were compared to results obtained on aliquots of the same sample by the radioimmunoassays (II and III). The correlation coefficients were: I vs. II 0.90, n=108; I vs. III 0.94, n=102; and II vs. III 0.95, n=158. Day-to-day precision (10 days) on a low control (1.3 mug/liter) and a high control 3.0 mg/liter), expressed as coefficients of variation, were: I, 13% and 7.8%, II, 4.0% and 4.7%; and III, 8.9% and 4.2%. Ten digoxin-supplemented samples (0-8 mug/liter) were analyzed by the three methods. Correlation coefficients were: supplemented sample vs. I, O.99; supplemented sample vs. II, 0.97; supplemented sample vs. III, 0.98.
采用两种不同的放射免疫分析法和一种酶免疫分析法对患者血清中的地高辛进行分析。将酶免疫分析法（I）获得的定量结果与用放射免疫分析法（II和III）对同一样品的等分试样分析得到的结果进行比较。相关系数如下：I与II为0.90，n = 108；I与III为0.94，n = 102；II与III为0.95，n = 158。以变异系数表示的低对照品（1.3微克/升）和高对照品（3.0毫克/升）的日间精密度（10天）分别为：I，13%和7.8%；II，4.0%和4.7%；III，8.9%和4.2%。用这三种方法对10份添加了地高辛的样品（0 - 8微克/升）进行分析。相关系数如下：添加样品与I为0.99；添加样品与II为0.97；添加样品与III为0.98。
