Homma Y, Imajo C, Takahashi S, Kawabe K, Aso Y
Department of Urology, University of Tokyo, Japan.
Scand J Urol Nephrol Suppl. 1994;157:27-30.
Age-related changes in the lower urinary tract function were investigated by means of symptomatology and urodynamics. In the symptom study subjectively normal 168 males and 101 females aged over 30 were administered a questionnaire regarding urinary symptoms. The prevalence of symptoms gradually advanced with age and nocturia more than 2 times was dramatically increased up to a half in those aged over 70. In the urodynamic study involving 65 males and 51 females with low symptom scores, significant reduction with advancing age was noted for maximum flow rate in both sexes (males: r = -0.295, p < 0.05, females: r = -0.591, p < 0.01) and maximum detrusor pressure in females (r = -0.513, p < 0.01). There was a significant increase in residual urine in males (r = 0.473, p < 0.05); otherwise no consistent changes in cystometry and urethral pressure profile related to aging were detected. These results indicate that urinary symptoms and urodynamic variables may change with age even in "normal" subjects, and warrant a careful interpretation of them in the elderly subjects.