Lukas W, Doepp M, Fäangewisch G L, Grebe S F
Nuklearmedizin. 1976 Oct;15(5):237-41.
Most of the programmes for the evaluation of radio in vitro tests proceed from the anticipation that the best method should give an approximation of standard values by a curve as perfect as possible. According to our experiences this demand, however, is not decisive for a good standard curve, as in principle all standard values can be incorrect. The application of relatively simple linearising transformations and an additional curve (recovery of a normal serum) guarantees the necessary precision in the programme described. After a short description of the contents of the system, the programme for the assessment of CPBA - methods is shown, by help of which the sample changer - calculator-system determines the absolute concentration of the substance to be measured. This makes the starting point for the more complex RIA programme which methodologically takes into consideration the special problems of these tests.
大多数用于评估体外放射测试的程序都基于这样一种预期，即最佳方法应通过尽可能完美的曲线给出标准值的近似值。然而，根据我们的经验，这一要求对于良好的标准曲线并非决定性因素，因为原则上所有标准值都可能是不正确的。应用相对简单的线性化变换和一条附加曲线（正常血清的回收率）可确保所描述程序的必要精度。在简要描述系统内容后，展示了用于评估CPBA方法的程序，借助该程序，样品更换器 - 计算器系统可确定待测物质的绝对浓度。这构成了更复杂的放射免疫分析程序的起点，该程序在方法上考虑了这些测试的特殊问题。
