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低剂量辐射——祸还是福?

Low dose radiation--a curse or a boon?

作者信息

Balaram P, Mani K S

机构信息

Regional Cancer Centre, Kerala, India.

出版信息

Natl Med J India. 1994 Jul-Aug;7(4):169-72.

PMID:7950949
Abstract

The increased use of nuclear technology has created fear in the minds of people regarding its possible adverse effects on living systems. This fear is heightened by press reports of nuclear fallouts and of high levels of natural background radiation in geographical areas in a number of countries. The International Commission on Radiological Protection and the United Nations Scientific Committee on the Effects of Atomic Radiation estimate the risk of cancer from high dose exposure to be 4.5% to 7.1% per sievert depending on the projection model used. However, when the exposure is to low dose background radiation, the available data does not show an increased risk. This is possibly due to the effectiveness of the inherent repair capacity of the living cell. These observations have given rise to the 'hormesis' hypothesis. Low dose radiation has in fact been found to be immunostimulatory and this is now being exploited as a possible treatment modality in cancer patients.

摘要

核技术使用的增加,在人们心中引发了对其可能对生命系统产生的不利影响的恐惧。一些国家地理区域内核辐射沉降物以及高水平天然本底辐射的新闻报道,加剧了这种恐惧。国际放射防护委员会和联合国原子辐射影响科学委员会估计,根据所使用的预测模型,每西弗特高剂量照射导致癌症的风险为4.5%至7.1%。然而,当暴露于低剂量本底辐射时,现有数据并未显示风险增加。这可能是由于活细胞固有修复能力的有效性。这些观察结果引发了“兴奋效应”假说。事实上,低剂量辐射已被发现具有免疫刺激作用,目前正被用作癌症患者可能的治疗方式。

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