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[低剂量电离辐射与对苯二酚对局部淋巴结体液免疫的单独及联合作用]

[Isolated and combined effects of low-level ionizing radiation and hydroquinone on the humoral immunity in the regional lymph nodes].

作者信息

Sharetskiĭ A N, Surinov B P, Abramova M R

出版信息

Radiats Biol Radioecol. 1994 Jul-Oct;34(4-5):495-501.

PMID:7951875
Abstract

The whole-body exposure of mice to 0.1 Gy gamma-radiation resulted in stimulation of T-cell dependent humoral immune response in lymph nodes. At the same time enhancement of susceptibility of immunocompetent cells to damaging effect of hydroquinone was observed. Under irradiation with doses of 0.5 or 1 Gy which cause dose-dependent immunosuppression, hydroquinone induced stimulation of antigen production.

摘要

将小鼠全身暴露于0.1 Gy的γ辐射下，会刺激淋巴结中T细胞依赖性体液免疫反应。与此同时，观察到免疫活性细胞对氢醌损伤作用的敏感性增强。在用0.5或1 Gy剂量照射导致剂量依赖性免疫抑制的情况下，氢醌会诱导抗原产生的刺激。

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