Chronic blepharitis, meibomitis and corneal lesions.

We have observed seven patients with longstanding complaints of ocular irritation who had blepharitis and/or meibomitis associated with corneal involvement. Corneal lesions varied from severe pannus formation, destruction of the limbal structure to marginal infiltrates and peripheral corneal melting. The corneal lesions did not regress until blepharitis was treated. The pathogenesis of chronic blepharitis with corneal involvement is discussed.