Winfree A T
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson 85721.
Science. 1994 Nov 11;266(5187):1003-6. doi: 10.1126/science.7973648.
Rotors or vortex action potentials with a diameter of about 1 centimeter and a rotation period of about 0.1 second occur in normal myocardium just before transition to fibrillation, a disorderly pattern of action potential propagation. Numerical models and corresponding mathematical analysis have recently suggested candidate mechanisms, all two-dimensional, for this transition from periodic electrical activity to something resembling turbulence. However, comparably recent experiments unanimously show that rotors, and the spiral waves they radiate, remain stably periodic in two-dimensional myocardium. This seeming paradox suggests a transition mediated through disorderly dynamics of the electrical vortex in three dimensions, as a "vortex filament."
在正常心肌中，就在转变为颤动（一种无序的动作电位传播模式）之前，会出现直径约1厘米、旋转周期约0.1秒的转子或涡旋动作电位。数值模型和相应的数学分析最近提出了一些二维的候选机制，用于解释从周期性电活动到类似湍流状态的这种转变。然而，相对近期的实验一致表明，转子及其辐射的螺旋波在二维心肌中保持稳定的周期性。这种看似矛盾的现象表明，这种转变是通过三维空间中作为“涡旋细丝”的电涡旋的无序动力学介导的。
