加拿大流感嗜血杆菌分离株的抗菌药敏性测定及其β-内酰胺酶特性。加拿大流感嗜血杆菌研究小组。
Determination of antimicrobial susceptibilities of Canadian isolates of Haemophilus influenzae and characterization of their beta-lactamases. Canadian Haemophilus Study Group.
作者信息
Scriver S R, Walmsley S L, Kau C L, Hoban D J, Brunton J, McGeer A, Moore T C, Witwicki E
机构信息
Department of Microbiology, Mount Sinai Hospital, University of Toronto, Ontario, Canada.
出版信息
Antimicrob Agents Chemother. 1994 Jul;38(7):1678-80. doi: 10.1128/AAC.38.7.1678.
Abstract
Susceptibility testing of 1,688 Haemophilus influenzae isolates found 484 ampicillin-resistant strains; 474 strains (28.4%) were beta-lactamase positive, and 5 strains (0.4%) were non-beta-lactamase producers. Restriction enzyme digestion of the beta-lactamase amplicon determined that, of 157 strains, 11 (7.0%) contained ROB-1 beta-lactamase and 146 (93.0%) contained a TEM-type beta-lactamase.
摘要
对1688株流感嗜血杆菌进行药敏试验，发现484株对氨苄西林耐药；474株（28.4%）β-内酰胺酶阳性，5株（0.4%）不产β-内酰胺酶。对β-内酰胺酶扩增子进行限制性酶切分析，结果显示，在157株菌株中，11株（7.0%）含有ROB-1β-内酰胺酶，146株（93.0%）含有TEM型β-内酰胺酶。
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