Iizuka M, Kaga E, Chiba M, Masamune O, Gerna G, Nakagomi O
Department of Microbiology, Akita University School of Medicine, Japan.
Arch Virol. 1994;135(3-4):427-32. doi: 10.1007/BF01310026.
Serotype G6 human rotavirus PA151 was examined by RNA-RNA hybridization in comparison with another G6 strain PA169 and two naturally-occurring G3 reassortants PCP5 and MZ58. PA151 possessed three gene segments that formed hybrids with AU-1 and seven gene segments that formed hybrids with bovine rotavirus NCDV. PA151 also possessed eight, 10 and 10 gene segments that formed hybrids with genomic RNAs from PA169, PCP5, and MZ58, respectively. Thus, PA151 was an intergenogroup reassortant formed in nature between members of the bovine and AU-1 genogroups and it shared a genome constellation with PA169, PCP5, and MZ58. These results suggest that naturally-occurring intergenogroup reassortants possessing such a genome constellation were perpetuated in human populations.
通过RNA - RNA杂交技术对血清型G6人轮状病毒PA151进行了检测，并与另一株G6病毒PA169以及两株天然存在的G3重配病毒PCP5和MZ58进行了比较。PA151拥有三个与AU - 1形成杂交体的基因片段以及七个与牛轮状病毒NCDV形成杂交体的基因片段。PA151还分别拥有八个、十个和十个与PA169、PCP5和MZ58的基因组RNA形成杂交体的基因片段。因此，PA151是牛基因组群和AU - 1基因组群成员之间在自然条件下形成的种间基因组重配病毒，并且它与PA169、PCP5和MZ58具有相同的基因组组合。这些结果表明，拥有这种基因组组合的天然种间基因组重配病毒在人群中得以延续。
