Gruner E, Steigerwalt A G, Hollis D G, Weyant R S, Weaver R E, Moss C W, Daneshvar M, Brenner D J
Institute for Medical Microbiology, University of Zurich, Switzerland.
J Clin Microbiol. 1994 Aug;32(8):1918-22. doi: 10.1128/jcm.32.8.1918-1922.1994.
Thirty strains of fermentative coryneform-like bacteria designated CDC fermentative coryneform group 3 and coryneform group 5 were compared biochemically by cellular fatty acid analysis and by DNA relatedness with the type strain of Dermabacter hominis, ATCC 49369. DNA from 22 strains of both CDC groups showed 69 to 96% relatedness (hydroxyapatite method) to labeled DNA from ATCC 49369 and to DNA from CDC group 3 strain G4964, and the strains are considered to belong to D. hominis. The remaining eight strains were genetically but not phenotypically differentiable from D. hominis. They were genetically heterogeneous, but hybridization results indicated that they probably belong to the genus Dermabacter. Thirteen of the 22 D. hominis strains and all 8 of the other Dermabacter strains had been isolated from blood, which indicates the pathogenic potential of this species and genus.
通过细胞脂肪酸分析以及与格氏皮肤杆菌模式菌株ATCC 49369进行DNA相关性比较,对30株发酵性棒状杆菌样细菌(分别指定为CDC发酵性棒状杆菌第3组和第5组)进行了生化特性比较。来自两个CDC组的22株菌株的DNA与来自ATCC 49369的标记DNA以及来自CDC第3组菌株G4964的DNA显示出69%至96%的相关性(羟基磷灰石法),这些菌株被认为属于格氏皮肤杆菌。其余8株菌株在遗传上与格氏皮肤杆菌有差异,但在表型上无法区分。它们在遗传上是异质的,但杂交结果表明它们可能属于皮肤杆菌属。22株格氏皮肤杆菌菌株中的13株以及所有8株其他皮肤杆菌菌株均从血液中分离得到,这表明该种和该属具有致病潜力。