N'gouemo P, Nguemby-Bina C, Baldy-Moulinier M
Laboratoire de Médecine Expérimentale, INSERM U249-CNRS UPR9008, Montpellier, France.
J Ethnopharmacol. 1994 Jul 22;43(3):161-6. doi: 10.1016/0378-8741(94)90037-x.
The ethanolic extract of the leaves of Maprounea africana (Euphorbiaceae), a medicinal plant in the Congolese traditional medicine, induced hypothermia and reduced the latency to the loss of the righting reflex and prolonged the sleeping time induced by pentobarbital in mice. It also significantly delayed the onset of clonic convulsions induced by pentylenetetrazole in mice. However, the extract did not affect either generalized convulsions induced by maximal electroshock and picrotoxin or limbic status epilepticus produced by pilocarpine and kainic acid.
