富含包被蛋白的内质网
Coatomer-rich endoplasmic reticulum.
作者信息
Orci L, Perrelet A, Ravazzola M, Amherdt M, Rothman J E, Schekman R
机构信息
Department of Morphology, University of Geneva Medical School, Switzerland.
出版信息
Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):11924-8. doi: 10.1073/pnas.91.25.11924.
We identify in normal cells the existence of two distinct sites of the transitional endoplasmic reticulum (ER), one housing the Sec23p protein complex (the classical transitional element), the other the coatomer protein complex (the coatomer-rich ER). Experimental conditions that reduce transport from the ER to the Golgi complex lead to the overexpression of this newly defined coatomer-rich ER.
我们在正常细胞中发现了内质网（ER）过渡区的两个不同位点，一个位点含有Sec23p蛋白复合物（经典的过渡元件），另一个位点含有COPII蛋白复合物（富含COPII的内质网）。减少从内质网到高尔基体复合物转运的实验条件会导致这种新定义的富含COPII的内质网过度表达。
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