Marinus M G, Konrad E B
Mol Gen Genet. 1976 Dec 22;149(3):273-7. doi: 10.1007/BF00268528.
F-prime heterogenotes of dam-3 bacteria segregate F-prime homogenotes at a frequency 30-200 times higher than the isogenic dam+ strain. A hyperrecombination mutant which shows increased recombination between chromosomal duplications was characterized as a dam mutant. The dam-3 allele causes a reduction in linkage of proximal unselected markers in transconjugants and increases the recombination frequency between a pair of closely linked markers. It is concluded that dam mutations confer a hyperrecombination phenotype to the cell.
dam-3细菌的F-prime异源基因座以比同基因dam+菌株高30至200倍的频率分离出F-prime同基因座。一个显示染色体重复间重组增加的超重组突变体被鉴定为dam突变体。dam-3等位基因导致转接合子中近端未选择标记的连锁减少，并增加一对紧密连锁标记间的重组频率。得出的结论是，dam突变赋予细胞超重组表型。
