Kienzle E, Wilms-Eilers S
Institute of Animal Nutrition, Tierärztliche Hochschule Hannover, Germany.
J Nutr. 1994 Dec;124(12 Suppl):2652S-2659S. doi: 10.1093/jn/124.suppl_12.2652S.
Six healthy adult cats were fed a basal minced beef meat and rice diet (one meal per day) with varying amounts or combinations of acidifying and alkalizing additives (ammonium chloride, calcium and sodium carbonate). The base excess in the food (mmol/kg dry matter) was calculated (data on food compounds in g/kg dry matter) as follows: base excess = 49.9Ca + 82.3Mg + 43.5Na + 25.6K-64.6P-13.4met-16.6cys-28.2Cl. Base excess in the experimental diets amounted to between +305 and -1079 mmol/kg dry matter. After an adaptation period of 5 d, urine and blood pH as well as water and mineral balance were determined in the cats over a 10-15-d period. The daily mean urine pH ranged between 6.1 and 7.8. There was a highly significant correlation between the base excess in the food and the mean urine pH. The regression line was linear down to a base excess in the diet of approximately -400 to -500 mmol/kg dry matter and a pH in the urine of 6.2. The postprandial increase of urine pH was suppressed either by large amounts of ammonium chloride (> 780 mmol/kg dry matter) alone or in combination with calcium carbonate but not in combination with sodium carbonate. The relationship between the decrease of the blood pH and the amount of ammonium chloride added to the diet was more marked than the relationship between blood pH and base excess in the food.(ABSTRACT TRUNCATED AT 250 WORDS)
给六只健康成年猫喂食以碎牛肉和大米为基础的日粮（每天一餐），并添加不同量或不同组合的酸化剂和碱化剂（氯化铵、碳酸钙和碳酸钠）。计算食物中的碱剩余量（mmol/kg干物质）（食物成分数据以g/kg干物质计）如下：碱剩余量=49.9×钙+82.3×镁+43.5×钠+25.6×钾-64.6×磷-13.4×蛋氨酸-16.6×半胱氨酸-28.2×氯。实验日粮中的碱剩余量为+305至-1079 mmol/kg干物质。经过5天的适应期后，在10至15天内测定猫的尿液和血液pH值以及水和矿物质平衡。每日平均尿液pH值在6.1至7.8之间。食物中的碱剩余量与平均尿液pH值之间存在高度显著的相关性。回归曲线在日粮碱剩余量约为-400至-500 mmol/kg干物质、尿液pH值为6.2时呈线性。单独大量添加氯化铵（>780 mmol/kg干物质）或与碳酸钙联合使用时，会抑制餐后尿液pH值的升高，但与碳酸钠联合使用时则不会。血液pH值的下降与日粮中添加的氯化铵量之间的关系比血液pH值与食物中碱剩余量之间的关系更为显著。（摘要截选至250字）
