Stensvold I, Jacobsen B K
National Health Screening Service, Oslo, Norway.
Cancer Causes Control. 1994 Sep;5(5):401-8. doi: 10.1007/BF01694753.
Relationships between coffee drinking and cancer incidence were examined in a 10-year complete follow-up of 21,735 men and 21,238 women aged 35-54 years. The study population participated in a cardiovascular screening in three countries in Norway during 1977-82. Data on coffee and smoking habits were based on information from a self-administered questionnaire. There was no association between coffee consumption and overall risk of cancer. A positive association was found between coffee drinking and risk of lung cancer, also after adjustment for age, cigarette smoking, and county of residence. Residual confounding by cigarette smoking and other lifestyle factors cannot be ruled out. A negative association was found with cancer of buccal cavity and pharynx and with malignant melanoma in women. No significant associations were found between coffee drinking and incidence of cancer of the pancreas or the bladder.
在对21735名年龄在35至54岁之间的男性和21238名女性进行的为期10年的完整随访中,研究了咖啡饮用与癌症发病率之间的关系。研究人群于1977年至1982年期间在挪威的三个国家参加了心血管筛查。关于咖啡和吸烟习惯的数据基于一份自填问卷提供的信息。咖啡消费与总体癌症风险之间没有关联。在对年龄、吸烟情况和居住县进行调整后,发现咖啡饮用与肺癌风险之间存在正相关。不能排除吸烟和其他生活方式因素造成的残余混杂影响。在女性中,发现咖啡饮用与口腔和咽喉癌以及恶性黑色素瘤之间存在负相关。未发现咖啡饮用与胰腺癌或膀胱癌发病率之间存在显著关联。