Ludwig S, Haustein A, Kaleta E F, Scholtissek C
Institut für Virologie, Universität Giessen, Germany.
Virology. 1994 Jul;202(1):281-6. doi: 10.1006/viro.1994.1344.
The most recent introduction of an avian influenza A virus without reassortment into mammals occurred in 1979 when H1N1 strains could be isolated from diseased pigs in northern Europe. This newly introduced avian virus formed a stable lineage in pigs and, in the meantime, spread all over Europe. In 1991 highly pathogenic H1N1 strains closely related to a contemporary swine virus were isolated from turkeys of a breeding farm near Bremen, Germany. Outbreaks in several farms in Germany, France, and the Netherlands indicate that the "avian-like" swine viruses can easily be reintroduced into an avian population causing severe economical losses.
最近一次未发生重配的甲型禽流感病毒传入哺乳动物的事件发生在1979年,当时在北欧患病猪中分离出了H1N1毒株。这种新传入的禽流感病毒在猪群中形成了一个稳定的谱系,与此同时,传播到了整个欧洲。1991年,在德国不来梅附近一个养殖场的火鸡中分离出了与当时一种猪病毒密切相关的高致病性H1N1毒株。德国、法国和荷兰多个农场爆发的疫情表明,“禽源样”猪病毒很容易重新传入禽群,造成严重的经济损失。