类风湿关节炎中的黏附分子：在发病机制中的作用及治疗前景
Adhesion molecules in rheumatoid arthritis: role in the pathogenesis and prospects for therapy.
作者信息
Pitzalis C, Kingsley G, Panayi G
机构信息
Rheumatology Unit, Guy's Hospital, London, United Kingdom.
出版信息
Ann Rheum Dis. 1994 May;53(5):287-8. doi: 10.1136/ard.53.5.287.
Abstract
The essential role played by cell adhesion and migration in the generation of chronic synovitis is now beyond doubt. Some of the beneficial effects of currently used drugs may be related to their ability to interfere with these mechanisms. The complexity of the process, however, means that there are many potential targets for therapeutic intervention and therefore further studies of the basic mechanisms are necessary to identify those which are most important.
摘要
细胞黏附与迁移在慢性滑膜炎形成过程中所起的关键作用现已毋庸置疑。当前所用药物的一些有益作用可能与其干扰这些机制的能力有关。然而，该过程的复杂性意味着存在许多潜在的治疗干预靶点，因此有必要对基本机制进行进一步研究，以确定那些最为重要的靶点。
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