Smith R W, Ellison D W, Jenkins E A, Gallagher P J, Cawley M I
Department of Rheumatology, Southampton University Hospitals, Southampton General Hospital, United Kingdom.
Ann Rheum Dis. 1994 May;53(5):327-30. doi: 10.1136/ard.53.5.327.
The case histories are reported of two patients with systemic lupus erythematosus (SLE) who developed fatal neurological involvement, each presenting with cerebellar and brainstem signs. Neuro-pathological changes were confined to the cerebellum and brainstem, with clear evidence of a small vessel vasculopathy. The predominant histological abnormalities were multiple perivascular haemorrhages in one case and classical vasculitic changes in the other.
报告了两例系统性红斑狼疮（SLE）患者的病例史，这两名患者均出现致命的神经系统受累，每人都表现出小脑和脑干体征。神经病理学改变局限于小脑和脑干，有明确的小血管血管病变证据。主要的组织学异常在一例中为多处血管周围出血，在另一例中为典型的血管炎改变。
