Schäffler L, Lüders H O, Morris H H, Wyllie E
Department of Neurology, Cleveland Clinic Foundation, Ohio 44195.
Epilepsia. 1994 May-Jun;35(3):525-8. doi: 10.1111/j.1528-1157.1994.tb02472.x.
In evaluation for surgical treatment of intractable psychomotor seizures originating in the language-dominant left mesiotemporal region, subdural grid electrodes were placed in 29 patients over the temporoparietal cortex and over the basotemporal region. In 13 patients, cortical stimulation of the basotemporal region showed interference with language processing. The most anterior border of the basotemporal language area began 1.1 cm posterior to the anterotemporal tip, and the most posterior margin of the language region was located 6.1 cm posterior to the temporal tip. The most lateral and the most mesial border were located 1.4 and 5.9 cm, respectively, from the lateral edge of the temporal lobe. The region in which language disturbance could be elicited included the inferior temporal gyrus, the fusiform (lateral and medial occipitotemporal) gyrus, and the parahippocampal gyrus. The basotemporal area most consistently involved with language function was the fusiform gyrus (60% of affected electrodes), followed by the inferotemporal (30%), and the parahippocampal (10%) gyri.
在对起源于左侧颞叶内侧语言优势区的顽固性精神运动性癫痫进行手术治疗评估时，对29例患者在颞顶叶皮质和颞底区域放置了硬膜下栅格电极。在13例患者中，颞底区域的皮质刺激显示对语言处理有干扰。颞底语言区的最前缘始于颞前极后方1.1厘米处，语言区的最后缘位于颞极后方6.1厘米处。最外侧和最内侧边界分别位于距颞叶外侧边缘1.4厘米和5.9厘米处。可引发语言障碍的区域包括颞下回、梭状（外侧和内侧枕颞）回和海马旁回。与语言功能最密切相关的颞底区域是梭状回（60%的受影响电极），其次是颞下（30%）和海马旁（10%）回。
