Rösch W
Medizinische Klinik am Krankenhaus Nordwest, Frankfurt a. M.
Schweiz Rundsch Med Prax. 1994 Jun 21;83(25-26):783-5.
Heartburn and epigastric pain are the leading symptoms of reflux disease. Next to other symptoms like pharyngeal burning, regurgitation and retrosternal pain, chronic hoarseness and coughing as well as angina pectoris symptoms may point towards a pathological reflux. In endoscopically verified reflux esophagitis proton pump inhibitors are the treatment of first choice. Aim of therapy is loss of symptoms, healing of epithelial defects and prevention of Barrett's esophagus. If a columnar epithelium-lined esophagus is seen, surveillance is recommended in one- or two-year intervals.
烧心和上腹部疼痛是反流性疾病的主要症状。除了咽部烧灼感、反流和胸骨后疼痛等其他症状外，慢性声音嘶哑、咳嗽以及心绞痛症状也可能提示病理性反流。在内镜检查确诊的反流性食管炎中，质子泵抑制剂是首选治疗药物。治疗的目标是症状消失、上皮缺损愈合以及预防巴雷特食管。如果发现食管内衬柱状上皮，则建议每隔一年或两年进行一次监测。
