• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Toxicology and pharmacological action of anabaena flos-aquae toxin.

作者信息

Carmichael W W, Biggs D F, Gorham P R

出版信息

Science. 1975 Feb 14;187(4176):542-4. doi: 10.1126/science.803708.

DOI:10.1126/science.803708
PMID:803708
Abstract

Calves, rats, ducks, and goldfish given lethal oral doses of bacteria-free lyophilized cell suspensions of toxic Anabaena flos-aquae died as a result of respiratory arrest. Experiments with selected animals and pharmacological preparations showed that the main effect of the toxin was production of a sustained postsynaptic depolarizing neuromuscular blockade.

摘要

相似文献

1
Toxicology and pharmacological action of anabaena flos-aquae toxin.
Science. 1975 Feb 14;187(4176):542-4. doi: 10.1126/science.803708.
2
The pharmacology of anatoxin-a(s), a neurotoxin produced by the freshwater cyanobacterium Anabaena flos-aquae NRC 525-17.由淡水蓝藻水华鱼腥藻NRC 525 - 17产生的神经毒素类毒素-a(s)的药理学。
Toxicon. 1986;24(5):425-34. doi: 10.1016/0041-0101(86)90074-7.
3
Purification of Aphanizomenon flos-aquae toxin and its chemical and physiological properties.
Toxicon. 1973 Jan;11(1):65-72. doi: 10.1016/0041-0101(73)90154-2.
4
Anticholinesterase poisonings in dogs from a cyanobacterial (blue-green algae) bloom dominated by Anabaena flos-aquae.犬类因以水华鱼腥藻为主的蓝藻（蓝绿藻）大量繁殖而发生抗胆碱酯酶中毒。
Am J Vet Res. 1988 Apr;49(4):500-3.
5
Biosynthesis of the tropane-related cyanobacterial toxin anatoxin-a: role of ornithine decarboxylase.
Phytochemistry. 1990;29(4):1107-11. doi: 10.1016/0031-9422(90)85413-a.
6
Triclosan toxicity in a model cyanobacterium (Anabaena flos-aquae): Growth, photosynthesis and transcriptomic response.三氯生对模式蓝藻（鱼腥藻）的毒性：生长、光合作用和转录组反应。
J Environ Sci (China). 2023 May;127:82-90. doi: 10.1016/j.jes.2022.03.039. Epub 2022 Apr 6.
7
Energy status and immune system alterations in Elliptio complanata after ingestion of cyanobacteria Anabaena flos-aquae.在摄入蓝藻鱼腥藻后，圆田螺椭圆珍珠贝的能量状态和免疫系统的改变。
Ecotoxicology. 2013 Apr;22(3):457-68. doi: 10.1007/s10646-012-1039-4. Epub 2013 Jan 26.
8
Two laboratory case studies on the oral toxicity to calves of the freshwater cyanophyte (blue-green alga) Anabaena flos-aquae NRC-44-1.关于淡水蓝藻（蓝绿藻）水华鱼腥藻NRC - 44 - 1对犊牛口腔毒性的两项实验室案例研究。
Can Vet J. 1977 Mar;18(3):71-5.
9
Effects of monosulfuron-ester on metabolic processes of nitrogen-fixing cyanobacteria Anabaena flos-aquae and Anabaena azotica.单嘧磺酯对固氮蓝藻水华鱼腥藻和固氮鱼腥藻代谢过程的影响。
Braz J Microbiol. 2017 Jul-Sep;48(3):544-550. doi: 10.1016/j.bjm.2016.10.028. Epub 2017 Mar 11.
10
Sodium channels blocked by aphantoxin obtained from the blue-green alga, Aphanizomenon flos-aquae.钠通道被从蓝绿藻水华鱼腥藻中获得的水华毒素所阻断。
Toxicon. 1982;20(2):513-6. doi: 10.1016/0041-0101(82)90017-4.

引用本文的文献

1
Airborne Cyanobacterial Toxins and Their Links to Neurodegenerative Diseases.空气中的蓝藻毒素及其与神经退行性疾病的联系。
Molecules. 2025 May 26;30(11):2320. doi: 10.3390/molecules30112320.
2
Transdisciplinary approaches for the study of cyanobacteria and cyanotoxins.用于研究蓝藻和蓝藻毒素的跨学科方法。
Curr Res Microb Sci. 2024 Oct 11;7:100289. doi: 10.1016/j.crmicr.2024.100289. eCollection 2024.
3
Cyanotoxins, biosynthetic gene clusters, and factors modulating cyanotoxin biosynthesis.蓝藻毒素、生物合成基因簇及调控蓝藻毒素生物合成的因素。
World J Microbiol Biotechnol. 2023 Jul 3;39(9):241. doi: 10.1007/s11274-023-03652-x.
4
Toxic Effects Produced by Anatoxin-a under Laboratory Conditions: A Review.实验室条件下生成的anatoxin-a 的毒性作用：综述。
Toxins (Basel). 2022 Dec 8;14(12):861. doi: 10.3390/toxins14120861.
5
Is the First Genetically Proved Anatoxin A Producer in Bulgarian Lakes and Reservoirs.保加利亚湖泊和水库中首个基因证实的毒蕈碱性乙酰胆碱酯酶抑制剂产生者。
Toxins (Basel). 2022 Nov 10;14(11):778. doi: 10.3390/toxins14110778.
6
Delineating the activity of the potent nicotinic acetylcholine receptor agonists (+)-anatoxin-a and (-)-hosieine-A.阐明强效烟碱型乙酰胆碱受体激动剂 (+)-anatoxin-a 和 (-)-hosieine-A 的活性。
Acta Crystallogr F Struct Biol Commun. 2022 Sep 1;78(Pt 9):313-323. doi: 10.1107/S2053230X22007762. Epub 2022 Aug 9.
7
Cobalt(I)-Catalyzed [6π + 2π] Cycloaddition of 1,2-Dienes and 1,3-Diynes to -Carbocholesteroxyazepine in the Synthesis of Previously Undescribed Heterofunctional 9-Azabicyclo[4.2.1]nonadi(tri)enes.钴（I）催化1,2 - 二烯与1,3 - 二炔与 - 碳胆甾氧基氮杂环庚三烯的[6π + 2π]环加成反应用于合成前所未有的杂功能9 - 氮杂双环[4.2.1]壬二（三）烯。
ACS Omega. 2021 Aug 12;6(33):21755-21763. doi: 10.1021/acsomega.1c03321. eCollection 2021 Aug 24.
8
Differential influences of (±) anatoxin-a on photolocomotor behavior and gene transcription in larval zebrafish and fathead minnows.（±）anatoxin-a对斑马鱼幼鱼和黑头呆鱼光运动行为及基因转录的差异影响。
Environ Sci Eur. 2021;33(1). doi: 10.1186/s12302-021-00479-x. Epub 2021 Mar 30.
9
Synthesis of New Functionally Substituted 9-Azabicyclo[4.2.1]nona-2,4,7-trienes by Cobalt(I)-Catalyzed [6π + 2π]-Cycloaddition of -Carbocholesteroxyazepine to Alkynes.新型功能取代的 9-氮杂双环[4.2.1]壬-2,4,7-三烯的钴（I）催化[6π + 2π]-环加成反应合成——β-碳杂胆固醇氧基氮杂环庚烷与炔烃。
Molecules. 2021 May 14;26(10):2932. doi: 10.3390/molecules26102932.
10
Geology and taphonomy of a unique tyrannosaurid bonebed from the upper Campanian Kaiparowits Formation of southern Utah: implications for tyrannosaurid gregariousness.来自犹他州南部坎帕阶晚期凯帕罗维茨组的独特暴龙科恐龙骨床的地质与埋藏学：对暴龙科群居习性的启示
PeerJ. 2021 Apr 19;9:e11013. doi: 10.7717/peerj.11013. eCollection 2021.