Morley R, Lister G, Leeson-Payne C, Lucas A
Infant and Child Nutrition Group, MRC Dunn Nutrition Unit, Cambridge.
Arch Dis Child. 1994 Jun;70(6):536-7. doi: 10.1136/adc.70.6.536.
Adults who were small at birth have been reported to have higher systolic blood pressure and risk of ischaemic heart disease in later life. Conversely, in 616 subjects of less than 34 weeks' gestation and 1850 g birth weight, systolic and diastolic blood pressures at 7.5 to 8 years of age decreased with decreasing weight for gestational age and were not related to birth weight. These data do not support the view that fetal growth retardation before 34 weeks programmes for increased blood pressure in later life.
据报道,出生时体型较小的成年人在晚年患收缩期高血压和缺血性心脏病的风险更高。相反,在616名孕周小于34周、出生体重1850克的受试者中,7.5至8岁时的收缩压和舒张压随着胎龄体重的降低而降低,且与出生体重无关。这些数据并不支持以下观点,即34周前的胎儿生长迟缓会导致晚年血压升高。