Hidiroglou N, McDowell L R, Batra T R, Papas A M
University of Florida, Animal Science Department, Gainesville 32611-0910.
Reprod Nutr Dev. 1994;34(3):273-8. doi: 10.1051/rnd:19940309.
Tissue alpha-tocopherol concentrations were determined in 40 lambs following oral supplementation of various forms of vitamin E. Lambs were allocated to 8 dietary groups of 5 animals each and supplemented with or without equimolar amounts (300 mg equivalence) of different vitamin E compounds daily for 60 d as follows: 1) control, no supplemental vitamin E; 2) D-alpha-tocopheryl acetate; 3) DL-alpha-tocopheryl acetate; 4) DL-alpha-tocopheryl nicotinate; 5) D-alpha-tocopheryl polyethylene glycol 1,000 succinate (TPGS); 6) DL-alpha-tocopheryl nicotinate+TPGS; 7) D-alpha-tocopheryl acetate+TPGS; and 8) D-alpha-tocopheryl succinate. At the end of the 60 d the lambs were killed and portions of adrenal, fat, heart, kidney, liver, lung, skeletal (brachiocephalicus and gluteus) muscles, pancreas and spleen were removed. Daily supplementation with various vitamin E compounds (equivalence) in lambs resulted in significant differences in tissue alpha-tocopherol concentration in heart, liver, gluteus medius muscle, and spleen. Correlations between the plasma and tissue alpha-tocopherol levels were highly significant for all tissues except adrenal, fat, and pancreas.
在给40只羔羊口服补充各种形式的维生素E后，测定了组织中的α-生育酚浓度。将羔羊分为8个日粮组，每组5只动物，每天补充或不补充等摩尔量（300毫克当量）的不同维生素E化合物，持续60天，具体如下：1）对照组，不补充维生素E；2）D-α-生育酚醋酸酯；3）DL-α-生育酚醋酸酯；4）DL-α-生育酚烟酸酯；5）D-α-生育酚聚乙二醇1000琥珀酸酯（TPGS）；6）DL-α-生育酚烟酸酯+TPGS；7）D-α-生育酚醋酸酯+TPGS；8）D-α-生育酚琥珀酸酯。在60天结束时，宰杀羔羊，取出肾上腺、脂肪、心脏、肾脏、肝脏、肺、骨骼肌（臂头肌和臀肌）、胰腺和脾脏的部分组织。在羔羊中每日补充各种维生素E化合物（当量）导致心脏、肝脏、臀中肌和脾脏的组织α-生育酚浓度存在显著差异。除肾上腺、脂肪和胰腺外，所有组织的血浆和组织α-生育酚水平之间的相关性都非常显著。
